Toxic epidermal necrolysis (Lyell’s syndrome): case report and review of the literature

نویسندگان

  • Mariusz Piechota
  • Maciej Banach
  • Aleksandra Kopeć
  • Jacek Rysz
  • Joanna Narbutt
چکیده

A case is described of a 59-year-old woman, who after oral intake of cefaclor presented with toxic epidermal necrolysis (TEN). Toxic epidermal necrolysis is characterized by widespread erythematous and bullous lesions on the skin caused by keratinocyte necrosis leading to exfoliation of epidermis, formation of erosions on mucous membranes and reactions from other organs. In the case of TEN diagnosis local lesions involve >30% of the body surface area. Appropriate local treatment with hydrogel dressings resulted in total healing of the area of exfoliated epidermis.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Reactivation of Cytomegalovirus in a Patient with Stevens-Johnson Syndrome-Toxic Epidermal Necrolysis

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe adverse cutaneous reactions to drugs. We describe the case of a 19 year old patient with SJS/TEN overlap syndrome, who developed severe interstitial pneumonia after she had received antiepileptic drugs. A cytomegalovirus infection was diagnosed by Real Time Polymerase Chain Reaction (RT-PCR) detection on Bronchoalveo...

متن کامل

An Epidemiological Study of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis during 2010-2015 at Shahid Faghihi Hospital, Shiraz, Iran

The Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are two ends of the spectrum of severe immunobullous state characterized by keratinocyte apoptosis. The present study aimed to draw attention to various epidemiological features of SJS and TEN diseases such as causative drugs, underlying diseases, duration of hospitalization, and types of treatment. The records of all patie...

متن کامل

Diclofenac-Induced Stevens-Johnson Syndrome: A Case Report

Drugs are an important cause of Stevens–Johnson syndrome(SJS) in about 95% of reports. 100 drugs have been reported as causes of SJS or toxic epidermal necrolysis (TEN). There are very few reports of SJS due to use of diclofenac. In this report we present a 65 year old lady who developed SJS after usage of diclofenac suppository.

متن کامل

CASE REPORT Treatment of Toxic Epidermal Necrolysis With Moisture-Retentive Ointment: A Case Report and Review of the Literature

Treatment of Toxic Epidermal Necrolysis With Moisture-Retentive Ointment: A Case Report and Review of the Literature BISHARA S. ATIYEH, MD, FACS, RUWAYDA DHAM, PHD, M FAYEZ YASSIN, MB, BCH, FRCS, AND KUSAI A. EL-MUSA, MD Division of Plastic and Reconstructive Surgery, American University of Beirut Medical Center, Beirut, Lebanon, Drug Research Center, Dubai, United Arab of Emirutes, and Jeddah,...

متن کامل

Survey on Etiology of Stevens-Johnson syndrome and Toxic Epidermal Necrolysis in Pediatric Patients: A Six-Year Study from Iran

Background Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are among the most severe dermatologic reactions to the drugs. Data about SJS and TEN among pediatric population especially in Iran is limited. This study aimed to investigate the clinical and para-clinical characteristics of pediatric patients with SJS/TEN. Materials and Methods From 2010 to 2016, all SJS and TEN c...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2009